Depressive Symptoms and Plasma Markers of Alzheimer's Disease and Neurodegeneration: A Coordinated Meta-Analysis of 8 Cohort Studies. Twait EL, Kamarioti M, Verberk IMW, Teunissen CE, Nooyens ACJ, Monique Verschuren WM, Visser PJ, Huisman M, Kok AAL, Eline Slagboom P, Beekman M, Vojinovic D, Lakenberg N, Arfan Ikram M, Schuurmans IK, Wolters FJ, Moonen JEF, Gerritsen L, van der Flier WM, Geerlings MI; NCDC Consortium. Am J Geriatr Psychiatry. 2024 Mar 11:S1064-7481(24)00274-4. doi: 10.1016/j.jagp.2024.03.004.
Plasma Markers of Alzheimer's Disease Pathology, Neuronal Injury, and Astrocytic Activation and MRI Load of Vascular Pathology and Neurodegeneration: The SMART-MR Study.Twait EL, Gerritsen L, Moonen JEF, Verberk IMW, Teunissen CE, Visser PJ, van der Flier WM, Geerlings MI; UCC SMART Study Group, the NCDC Consortium. J Am Heart Assoc. 2024 Feb 20;13(4):e032134. doi: 10.1161/JAHA.123.032134
Association of amyloid-beta with depression or depressive symptoms in older adults without dementia: a systematic review and meta-analysis Twait EL, Wu JH, Kamarioti M, Basten M, van der Flier WM, Gerritsen L, Geerlings MI. Transl Psychiatry. 2024 Jan 15;14(1):25. doi: 10.1038/s41398-024-02739-9.
A taxonomy of threat and soothing influences in rheumatic and musculoskeletal diseases and central sensitivity syndromes. Hijne K, Gerritsen L, Pinto AM, da Silva JAP, van Eck van der Sluijs JF, Geenen R.
Int J Clin Health Psychol. 2024 Jan-Mar;24(1):100420. doi: 10.1016/j.ijchp.2023.100420
Positive future thinking without task-relevance increases anxiety and frontal stress regulation. Montijn ND, Gerritsen L, van Son D, Engelhard IM (2023). Biol Psychology. doi: https://doi.org/10.1016/j.biopsycho.2023.108620
Psychosocial factors and hippocampal subfields: The Medea-7T study. Twait EL, Blom K, Koek HL, Zwartbol MHT, Ghaznawi R, Hendrikse J, Gerritsen L, Geerlings MI(2022); UCC SMART. Hum Brain Mapp. Dec 30. doi: 10.1002/hbm.26185.
Late-life depression, allostatic load and risk for dementia. The AGES-Reykjavik study. er from the pe
Twait EL, Basten M, Gerritsen L, GudnasonV, Launer LJ, Geerlings MI. (2022). Psychoneuroendocrinology. Nov 17;148:105975. doi: 10.1016/j.psyneuen.2022.105975.
Stable anxiety and depression trajectories in latte adolescence for oral contraceptive users. disorder Doornweerd AM, Branje S, Nelemans SA, Meeus WHJ, Montoya ER, Engelhard IM, Baas JMP, Gerritsen L.Front Psychiatry. May 23;13:799470. doi: 10.3389/fpsyt.2022.799470.
Hijne K, van Eck van der Sluijs JF, van Broeckhuysen-Kloth SAM, Lucassen PLBJ, Reinders M, Tak LM, Gerritsen L, Geenen R. J (2022) Psychosom Res. 2022 Mar;154:110712. doi: 10.1016/j.jpsychores.2021.110712.
Depression and Dementia: The Role of Cortisol and Vascular Brain Lesions. AGES-Reykjavik Study. Gerritsen L, Twait EL, Jonsson PV, Gudnason V, Launer LJ, Geerlings MI. J Alzheimers Dis. 2021 Dec 21. doi: 10.3233/JAD-215241.
****This articlewas chosen as one of the most important and clinically relevant papers of the year 2022 and was therefore featured in their Highlights book***
Depressive symptom profiles predict dementia onset and brain pathology in older persons. The AGES-Reykjavik study. Gerritsen L, Sigurdsson S, Jonsson PV, Gudnason V, Launer LJ, Geerlings MI. Neurobiol Aging. 2021 Nov 27;111:14-23.
doi: 10.1016/j.neurobiolaging.2021.09.025.
Scarth M, Vonk JMJ, Gerritsen L, Geerlings MI. Journal of Affective Disorders. 2022 Feb; 299; 559-567.
Montijn ND, Gerritsen L, Engelhard IM. Psychol Sci. 2021 Apr;32(4):587-597.
doi: 10.1177/0956797620972491.
Fear of the coronavirus (COVID-19): Predictors in an online study conducted in March 2020.
Mertens G, Gerritsen L, Duijndam S, Salemink E, Engelhard IM. J Anxiety Disord. 2020 Aug;74:102258. doi: 10.1016/j.janxdis.2020.102258.
The Association of Individual Changes in Stressful Life Events and Telomere Length Over Time in Twins 50 Years and Older.
Gerritsen L, Hägg S, Reynolds CA, Pedersen NL. Psychosom Med. 2020 Jul/Aug;82(6):614-622.
doi: 10.1097/PSY.0000000000000826.
Prospective biomarkers of major depressive disorder: a systematic review and meta-analysis. Kennis M, Gerritsen L, van Dalen M, Williams A, Cuijpers P, Bockting C. Mol Psychiatry. 2020 Feb;25(2):321-338. doi: 10.1038/s41380-019-0585-z.
Long-term glucocorticoid levels measured in hair in patients with depressive and anxiety disorders. Gerritsen L, Staufenbiel SM, Penninx BWJH, van Hemert AM, Noppe G, de Rijke YB, van Rossum EFC. Psychoneuroendocrinology. 2019 Mar;101:246-252.
doi: 10.1016/j.psyneuen.2018.11.019.
Reply to: Late-Life Depression, Cortisol, and the Hippocampus: On the Need to Consider Depressive, Hippocampal, and Pharmacological Complexities. Geerlings MI, Gerritsen L. Biol Psychiatry. 2018 Jan 1;83(1):e25. doi: 10.1016/j.biopsych.2017.07.002.
HPA Axis Genes, and Their Interaction with Childhood Maltreatment, are Related to Cortisol Levels and Stress-Related Phenotypes.
Gerritsen L, Milaneschi Y, Vinkers CH, van Hemert AM, van Velzen L, Schmaal L, Penninx BW. Neuropsychopharmacology. 2017 Nov;42(12):2446-2455.
Influence of Negative Life Events and Widowhood on Risk for Dementia.
Gerritsen L, Wang HX, Reynolds CA, Fratiglioni L, Gatz M, Pedersen NL. Am J Geriatr Psychiatry. 2017 Jul;25(7):766-778. doi: 10.1016/j.jagp.2017.02.009.
Hägg S, Zhan Y, Karlsson R, Gerritsen L, Ploner A, van der Lee SJ, Broer L, Deelen J, Marioni RE, Wong A, Lundquist A, Zhu G, Hansell NK, Sillanpää E, Fedko IO, Amin NA, Beekman M, de Craen AJM, Degerman S, Harris SE, Kan KJ, Martin-Ruiz CM, Montgomery GW; NeuroCHARGE Cognitive Working Group, Adolfsson AN, Reynolds CA, Samani NJ, Suchiman HED, Viljanen A, von Zglinicki T, Wright MJ, Hottenga JJ, Boomsma DI, Rantanen T, Kaprio JA, Nyholt DR, Martin NG, Nyberg L, Adolfsson R, Kuh D, Starr JM, Deary IJ, Slagboom PE, van Duijn CM, Codd V, Pedersen NL. Transl Psychiatry. 2017 Apr 18;7(4):e1100. doi: 10.1038/tp.2017.73.
Late-Life Depression, Hippocampal Volumes, and Hypothalamic-Pituitary-Adrenal Axis Regulation: A Systematic Review and Meta-analysis.
Geerlings MI, Gerritsen L. Biol Psychiatry. 2017 Sep 1;82(5):339-350.
doi: 10.1016/j.biopsych.2016.12.032.
Hippocampal volume and the course of depressive symptoms over eight years of follow-up. Buddeke J, Kooistra M, Zuithoff NP, Gerritsen L, Biessels GJ, van der Graaf Y, Geerlings MI; SMART Study Group. Acta Psychiatr Scand. 2017 Jan;135(1):78-86. doi: 10.1111/acps.12662.
Berglund K, Reynolds CA, Ploner A, Gerritsen L, Hovatta I, Pedersen NL, Hägg S. Aging (Albany NY). 2016 Jul;8(7):1398-415. doi: 10.18632/aging.100995.
Erratum to "Subfields of the hippocampal formation at 7T MRI: In vivo volumetric assessment"
Wisse LEM, Gerritsen L, Zwanenburg JJM, Kuijf HJ, Luijten PR, Biessels GJ, Geerlings MI. Neuroimage. 2016 Jan 15;125:1176-1177.
doi: 10.1016/j.neuroimage.2015.10.054.
Antemortem Prediction of Braak Stage.
Carlson JO, Gatz M, Pedersen NL, Graff C, Nennesmo I, Lindström AK, Gerritsen L. J Neuropathol Exp Neurol. 2015 Nov;74(11):1061-70. doi: 10.1097/NEN.0000000000000251.
Childhood maltreatment modifies the relationship of depression with hippocampal volume. Gerritsen L, van Velzen L, Schmaal L, van der Graaf Y, van der Wee N, van Tol MJ, Penninx B, Geerlings M. Psychol Med. 2015 Dec;45(16):3517-26. doi: 10.1017/S0033291715001415.
Genetics of brain and cognitive aging: introduction to the special issue of Neuropsychology Review. Pedersen NL, Gerritsen L. Neuropsychol Rev. 2015 Mar;25(1):1-2. doi: 10.1007/s11065-015-9282-0.
Mineralocorticoid receptor haplotypes sex-dependently moderate depression susceptibility following childhood maltreatment.
Vinkers CH, Joëls M, Milaneschi Y, Gerritsen L, Kahn RS, Penninx BW, Boks MP. Psychoneuroendocrinology. 2015 Apr;54:90-102. doi: 10.1016/j.psyneuen.2015.01.018.
Genetics and underlying pathology of dementia.
Ferencz B, Gerritsen L. Neuropsychol Rev. 2015 Mar;25(1):113-24. doi: 10.1007/s11065-014-9276-3.
Gerritsen L, Kalpouzos G, Westman E, Simmons A, Wahlund LO, Bäckman L, Fratiglioni L, Wang HX. Psychol Med. 2015 Apr;45(6):1219-28. doi: 10.1017/S0033291714002293.
The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: evidence of validity.
Frisoni GB, Jack CR Jr, Bocchetta M, Bauer C, Frederiksen KS, Liu Y, Preboske G, Swihart T, Blair M, Cavedo E, Grothe MJ, Lanfredi M, Martinez O, Nishikawa M, Portegies M, Stoub T, Ward C, Apostolova LG, Ganzola R, Wolf D, Barkhof F, Bartzokis G, DeCarli C, Csernansky JG, deToledo-Morrell L, Geerlings MI, Kaye J, Killiany RJ, Lehéricy S, Matsuda H, O'Brien J, Silbert LC, Scheltens P, Soininen H, Teipel S, Waldemar G, Fellgiebel A, Barnes J, Firbank M, Gerritsen L, Henneman W, Malykhin N, Pruessner JC, Wang L, Watson C, Wolf H, deLeon M, Pantel J, Ferrari C, Bosco P, Pasqualetti P, Duchesne S, Duvernoy H, Boccardi M; EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Volumetry and for the Alzheimer's Disease Neuroimaging Initiative. Alzheimers Dement. 2015 Feb;11(2):111-25. doi: 10.1016/j.jalz.2014.05.1756.
Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance.
Boccardi M, Bocchetta M, Apostolova LG, Barnes J, Bartzokis G, Corbetta G, DeCarli C, deToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duvernoy H, Duchesne S, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on the Harmonized Protocol for Manual Hippocampal Segmentation. Alzheimers Dement. 2015 Feb;11(2):126-38. doi: 10.1016/j.jalz.2014.02.009.
Vogel S, Gerritsen L, van Oostrom I, Arias-Vásquez A, Rijpkema M, Joëls M, Franke B, Tendolkar I, Fernández G. Psychoneuroendocrinology. 2014 Feb;40:181-90. doi: 10.1016/j.psyneuen.2013.11.010.
Lacunar infarcts in deep white matter are associated with higher and more fluctuating depressive symptoms during three years follow-up.
Grool AM, Gerritsen L, Zuithoff NP, Mali WP, van der Graaf Y, Geerlings MI. Biol Psychiatry. 2013 Jan 15;73(2):169-76. doi: 10.1016/j.biopsych.2012.08.024.
Loss of entorhinal cortex and hippocampal volumes compared to whole brain volume in normal aging: the SMART-Medea study.
Knoops AJ, Gerritsen L, van der Graaf Y, Mali WP, Geerlings MI. Psychiatry Res. 2012 Jul 30;203(1):31-7. doi: 10.1016/j.pscychresns.2011.12.002.
Subfields of the hippocampal formation at 7 T MRI: in vivo volumetric assessment.
Wisse LE, Gerritsen L, Zwanenburg JJ, Kuijf HJ, Luijten PR, Biessels GJ, Geerlings MI. Neuroimage. 2012 Jul 16;61(4):1043-9. doi: 10.1016/j.neuroimage.2012.03.023.
Sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume.
Everaerd D, Gerritsen L, Rijpkema M, Frodl T, van Oostrom I, Franke B, Fernández G, Tendolkar I. Neuropsychopharmacology. 2012 Jul;37(8):1848-55. doi: 10.1038/npp.2012.32.
Interaction between BDNF Val66Met and childhood stressful life events is associated to affective memory bias in men but not women.
van Oostrom I, Franke B, Rijpkema M, Gerritsen L, Arias-Vásquez A, Fernández G, Tendolkar I. Biol Psychol. 2012 Jan;89(1):214-9. doi: 10.1016/j.biopsycho.2011.10.012.
Amygdala to hippocampal volume ratio is associated with negative memory bias in healthy subjects. Gerritsen L, Rijpkema M, van Oostrom I, Buitelaar J, Franke B, Fernández G, Tendolkar I. Psychol Med. 2012 Feb;42(2):335-43. doi: 10.1017/S003329171100122X.
BDNF Val66Met genotype modulates the effect of childhood adversity on subgenual anterior cingulate cortex volume in healthy subjects.
Gerritsen L, Tendolkar I, Franke B, Vasquez AA, Kooijman S, Buitelaar J, Fernández G, Rijpkema M. Mol Psychiatry. 2012 Jun;17(6):597-603. doi: 10.1038/mp.2011.51.
Depression, hypothalamic pituitary adrenal axis, and hippocampal and entorhinal cortex volumes--the SMART Medea study.
Gerritsen L, Comijs HC, van der Graaf Y, Knoops AJ, Penninx BW, Geerlings MI. Biol Psychiatry. 2011 Aug 15;70(4):373-80. doi: 10.1016/j.biopsych.2011.01.029.
Basal hypothalamic pituitary adrenal axis activity and hippocampal volumes: the SMART-Medea study. Knoops AJ, Gerritsen L, van der Graaf Y, Mali WP, Geerlings MI. Biol Psychiatry. 2010 Jun 15;67(12):1191-8. doi: 10.1016/j.biopsych.2010.01.025.
Personality characteristics and hypothalamic-pituitary-adrenal axis regulation in older persons. Gerritsen L, Geerlings MI, Bremmer MA, Beekman AT, Deeg DJ, Penninx BW, Comijs HC. Am J Geriatr Psychiatry. 2009 Dec;17(12):1077-84. doi: 10.1097/JGP.0b013e3181bd1be6.
The association between serum cortisol and cognitive decline in older persons.
Comijs HC, Gerritsen L, Penninx BW, Bremmer MA, Deeg DJ, Geerlings MI. Am J Geriatr Psychiatry. 2010 Jan;18(1):42-50. doi: 10.1097/JGP.0b013e3181b970ae.
Early and late life events and salivary cortisol in older persons.
Gerritsen L, Geerlings MI, Beekman AT, Deeg DJ, Penninx BW, Comijs HC. Psychol Med. 2010 Sep;40(9):1569-78. doi: 10.1017/S0033291709991863.
Salivary cortisol, APOE-ε4 allele and cognitive decline in a prospective study of older persons. Gerritsen L, Comijs HC, Deeg DJ, Penninx BW, Geerlings MI. Neurobiol Aging. 2011 Sep;32(9):1615-25. doi: 10.1016/j.neurobiolaging.2009.09.007.
Visual rating of the hippocampus in non-demented elders: Does it measure hippocampal atrophy or other indices of brain atrophy? The SMART-MR study.
Knoops AJ, van der Graaf Y, Appelman AP, Gerritsen L, Mali WP, Geerlings MI. Hippocampus. 2009 Nov;19(11):1115-22. doi: 10.1002/hipo.20575.
Recognition of facial expressions of different emotional intensities in patients with frontotemporal lobar degeneration.
Kessels RP, Gerritsen L, Montagne B, Ackl N, Diehl J, Danek A. Behav Neurol. 2007;18(1):31-6. doi: 10.1155/2007/868431.
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